⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL28022526 | 0.95 | — | — | |
| SCHEMBL28166931 | 0.69 | — | — | |
| SCHEMBL446759 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28176836 | 0.67 | — | — | |
| SCHEMBL28267747 | 0.67 | — | — | |
| SCHEMBL6422365 | 0.65 | — | — | |
| SCHEMBL366678 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL31508618 | 0.65 | — | — | |
| SCHEMBL2056747 | 0.65 | — | — | |
| SCHEMBL179728 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026032-A | The manufacture method of optical activity 4- carbamoyl -2,6- 3,5-dimethylphenyl alanine derivatives | 株式会社钟化 | 2018-05-11 | — | — | CN | claimed |
| CN-106164044-B | Process for producing 1-arylimino-2-vinylcyclopropanecarboxylic acid derivative | 株式会社钟化 | 2018-05-04 | — | — | CN | claimed |
| CN-106164044-A | Process for producing 1-arylimino-2-vinylcyclopropanecarboxylic acid derivative | 株式会社钟化 | 2016-11-23 | — | — | CN | claimed |
| CN-112969504-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-107848963-B | Acid-resistant alkali-producing agent and/or radical-producing agent, and curable resin composition containing same | 富士胶片和光纯药株式会社 | 2020-11-03 | — | — | CN | disclosed |
| CN-108047267-A | Miscellaneous two ring [3.3.3] the hendecane compound of -5- bromines (hydrogen) of 1- azepine -5- germanium and its synthetic method | 中国科学技术大学 | 2018-05-18 | — | — | CN | disclosed |
| CN-108026032-A | The manufacture method of optical activity 4- carbamoyl -2,6- 3,5-dimethylphenyl alanine derivatives | 株式会社钟化 | 2018-05-11 | — | — | CN | disclosed |
| CN-107849018-A | Bridged piperazine derivatives | 安斯泰来制药株式会社 | 2018-03-27 | — | — | CN | disclosed |
| CN-105403603-B | A kind of preparation method and applications of optical electro-chemistry aptamers sensing electrode | 江苏大学 | 2018-02-27 | — | — | CN | disclosed |
| CN-105073715-B | The derovatives of dihydrogen dazin 3,5 | 中外制药株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-104761578-B | Based on rhodium tetraphenylporphyrin azepine fluorine boron two pyrroles's near infrared absorption phosphor material and its preparation method and purposes | 南京大学 | 2017-03-08 | — | — | CN | disclosed |
| US-7982032-B2 | reacting Dibenzo[b,f]azepine-5-carbonylchloride with alkali metal methoxide to yield 10-Methoxy-dibenz[b,f]azepine | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2011-07-19 | — | — | US | disclosed |
| US-20080269480-A1 | Process for the Preparation of 10,11-Dihydro-10-Oxo-5H-Dibenz[B,F] Azepine-5-Carboxamide | MUTHUKUMARAN MANDAKINI | 2008-10-30 | — | — | US | disclosed |
| WO-2005096709-A2 | A PROCESS FOR THE PREPARATION OF 10,11-DIHYDRO-10-OXO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2005-10-20 | — | — | WO | disclosed |
| CN-1009931-B | The method for preparing glycerol ether phosphatides | HOFFMANN LA ROCHE (CH) | 1990-10-10 | — | — | CN | disclosed |
| CN-85103123-A | The method for preparing glycerol ether phosphatides | — | 1986-10-22 | — | — | CN | disclosed |