Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157996 | 0.76 | KDM4E (0.46) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL30386272 | 0.72 | TDP1 (0.44) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL20740270 | 0.72 | TDP1 (0.44) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL26259380 | 0.68 | KDM4E (0.48) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL2239779 | 0.67 | ALDH1A1 (0.40) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL7760207 | 0.67 | IDO1 (0.44) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL7101479 | 0.66 | TAAR1 (0.47) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL26259566 | 0.64 | POLB (0.48) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL1310537 | 0.63 | KMT2A (0.62) | KDM4EKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL19662084 | 0.63 | TDP1 (0.47) | KDM4EKMT2AMAPTHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898633-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127504-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |