Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425773 | 0.90 | TBXAS1 (0.60) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL13007775 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL13007784 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL22268978 | 0.86 | TBXAS1 (0.63) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL11053462 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL17581952 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL8389532 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL502382 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL18469637 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A | |
| SCHEMBL5148219 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TBXAS1MAPK1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025064718-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| EP-3898630-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126954-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| CN-1297554-C | Amido ether substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2007-01-31 | — | — | CN | disclosed |
| CN-1252070-C | Urea substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-04-19 | — | — | CN | disclosed |
| CN-1247575-C | Sulfonamide ether substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-03-29 | — | — | CN | disclosed |
| CN-1537111-A | Urea substituted imidazoquinoline ethers | 3M | 2004-10-13 | — | — | CN | disclosed |
| CN-1511155-A | Sulfonamide ether substituted imidazoquinolines | 3M | 2004-07-07 | — | — | CN | disclosed |
| CN-1487939-A | Amido ether substituted imidazoquinolines | 3M | 2004-04-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129021-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | MYC, KRAS, NRAS | ALDH1A1 2630/4885TBXAS1 2678/4885MAPK1 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.