SCHEMBL2212836

SCHEMBL2212836

ClCc1nnnn1-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 14/20 0.69
LMNA P02545 5/20 0.69
NPSR1 Q6W5P4 3/20 0.69
L3MBTL1 Q9Y468 2/20 0.69
HTT P42858 3/20 0.60
PKM P14618 2/20 0.60
NLRP3 Q96P20 1/20 0.60
KMT2A Q03164 2/20 0.54
THRB P10828 1/20 0.54
HPGD P15428 2/20 0.53
MAPT P10636 2/20 0.53
CCR6 P51684 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
HSD11B1 P28845 5/20 0.53
TSHR P16473 2/20 0.51
MEN1 O00255 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4675275 0.84 HSD11B1 (0.64) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL15452739 0.84 HTT (0.64) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL25250647 0.83 ALDH1A1 (0.72) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL97009 0.81 HTT (0.60) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL156901 0.81 HTT (0.60) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL27959558 0.81 HTT (0.60) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL10934021 0.81 HTT (0.60) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL5545310 0.81 HTT (0.60) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL97010 0.81 HTT (0.60) ALDH1A1LMNANPSR1L3MBTL1HTT
SCHEMBL4405904 0.79 HSD11B1 (0.59) ALDH1A1LMNANPSR1L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002355-A1 PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2024-01-04 US disclosed
EP-4247799-A1 NEW PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-09-27 EP disclosed
CN-116635372-A Novel process for producing tetrazole derivatives 豪夫迈·罗氏有限公司 2023-08-22 CN disclosed
WO-2022106669-A1 NEW PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2022-05-27 WO disclosed
WO-2022106669-A1 NEW PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2022-05-27 WO disclosed
EP-1952918-B1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO (JP) 2013-05-22 EP disclosed
CN-101287566-B Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film TOYO INK MFG CO 2012-05-23 CN disclosed
US-7981327-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG. CO. LTD. (JP) 2011-07-19 US disclosed
US-20090258202-A1 Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) 2009-10-15 US disclosed
CN-101287566-A Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film TOYO INK MFG CO (JP) 2008-10-15 CN disclosed
EP-1952918-A1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM Toyo Ink Mfg. Co., Ltd (JP) 2008-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002355-A1 PROCESS FOR THE MANUFACTURE OF TETRAZOLE DERIVATIVES CYP2F1, CYP1A2, CYP3A4 ALDH1A1 173/4885LMNA 3240/4885NPSR1 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.