Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 5/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366778 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRERN1SMN1; SMN2GRIA1 | |
| SCHEMBL20607355 | 0.80 | ERN1 (0.45) | ALDH1A1TSHRERN1CYP3A4 | |
| SCHEMBL9821011 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHRERN1PRKDCSMN1; SMN2 | |
| SCHEMBL19641559 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRERN1PRKDCSMN1; SMN2 | |
| SCHEMBL30065195 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRERN1PRKDCSMN1; SMN2 | |
| SCHEMBL22768246 | 0.75 | ERN1 (0.35) | ERN1PRKDC | |
| SCHEMBL28524025 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRERN1SMN1; SMN2GRIA1 | |
| SCHEMBL25250329 | 0.75 | ERN1 (0.39) | ALDH1A1TSHRERN1PRKDCLMNA | |
| SCHEMBL1144801 | 0.75 | ERN1 (0.44) | ALDH1A1TSHRERN1PRKDCSMN1; SMN2 | |
| SCHEMBL31088734 | 0.75 | ERN1 (0.44) | ALDH1A1TSHRERN1PRKDCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407725-B2 | Selective fluorescent probe for aldehyde dehydrogenase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200199092-A1 | SELECTIVE FLUORESCENT PROBE FOR ALDEHYDE DEHYDROGENASE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407725-B2 | Selective fluorescent probe for aldehyde dehydrogenase | ALDH1A1, ALDH3A1, ALDH16A1 | ALDH1A1 1/4885TSHR 3929/4885ERN1 1974/4885 |
| US-20200199092-A1 | SELECTIVE FLUORESCENT PROBE FOR ALDEHYDE DEHYDROGENASE | ALDH1A1, ALDH3A1, ALDH16A1 | ALDH1A1 1/4885TSHR 3929/4885ERN1 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.