Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 6/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 4/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22148987 | 0.87 | MGLL (0.41) | JMJD6MGLLIDO1CYP3A4 | |
| SCHEMBL22149105 | 0.86 | JMJD6 (0.39) | JMJD6RETMGLLIDO1MAPT | |
| SCHEMBL22149085 | 0.84 | MGLL (0.38) | RETMGLLSPRTTRPOLB | |
| SCHEMBL22149067 | 0.83 | ABCB1 (0.44) | JMJD6MGLLIDO1ABCB1MAPT | |
| SCHEMBL22149081 | 0.81 | IRAK4 (0.42) | RETMGLL | |
| SCHEMBL22149087 | 0.81 | IRAK4 (0.38) | RETMGLL | |
| SCHEMBL22149001 | 0.81 | MET (0.50) | RET | |
| SCHEMBL22149057 | 0.80 | SRC (0.41) | RETPOLB | |
| SCHEMBL22149107 | 0.80 | SRC (0.42) | RETSPRPOLB | |
| SCHEMBL22129173 | 0.78 | IDO1 (0.40) | IDO1MAPTGSK3BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |