Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975599 | 0.81 | KDM4E (0.51) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL29373485 | 0.79 | TLR9 (0.47) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL31000102 | 0.79 | NPC1 (0.47) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL753696 | 0.79 | NPC1 (0.47) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL22529077 | 0.79 | METTL3 (0.47) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL13050350 | 0.77 | TLR9 (0.46) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL13080337 | 0.77 | METTL3 (0.49) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL29373194 | 0.76 | NPC1 (0.47) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL22129373 | 0.75 | PIK3CG (0.55) | TLR9TLR7NPC1RAB9AKDM4E | |
| SCHEMBL7268498 | 0.74 | PTGS1 (0.54) | TLR9TLR7NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349093-B | 5, 6-bicyclic compounds as WNT signal pathway inhibitors and medical application thereof | 汇瀚医疗科技有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-111349093-A | 5, 6-bicyclic compounds as WNT signal pathway inhibitors and medical application thereof | 汇瀚医疗科技有限公司 | 2020-06-30 | — | — | CN | disclosed |
| WO-2020125759-A1 | COMPOUND AS WNT SIGNAL PATHWAY INHIBITOR AND MEDICAL USE THEREOF | 汇瀚医疗科技有限公司 | 2020-06-25 | — | — | WO | disclosed |