Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 13/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31082292 | 0.82 | SUV39H2 (0.37) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL7975599 | 0.81 | KDM4E (0.51) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL22129495 | 0.79 | TLR9 (0.52) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL29373485 | 0.79 | TLR9 (0.47) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL753696 | 0.79 | NPC1 (0.47) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL13050350 | 0.77 | TLR9 (0.46) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL13080337 | 0.77 | METTL3 (0.49) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL18569907 | 0.77 | SMN1; SMN2 (0.57) | NPC1RAB9AKDM4EPKMTP53 | |
| SCHEMBL25045598 | 0.76 | SMN1; SMN2 (0.36) | NPC1RAB9AKDM4EPKMTLR9 | |
| SCHEMBL22529077 | 0.76 | METTL3 (0.47) | NPC1RAB9AKDM4EPKMTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| CN-118613480-A | Polycyclic IRAK and FLT3 inhibiting compounds and uses thereof | 儿童医院医学中心 | 2024-09-06 | — | — | CN | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |