Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 14/20 | 0.53 |
| ▸ | KDR | P35968 | 8/20 | 0.53 |
| ▸ | CDK4 | P11802 | 3/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.53 |
| ▸ | TTK | P33981 | 2/20 | 0.53 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.53 |
| ▸ | STK25 | O00506 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458766 | 0.86 | CHEK1 (0.67) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL2458765 | 0.86 | CHEK1 (0.67) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL11924702 | 0.85 | CHEK1 (0.55) | CHEK1KDRCDK4FGFR1AURKA | |
| SCHEMBL18813990 | 0.84 | CHEK1 (0.53) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL18844727 | 0.84 | CHEK1 (0.53) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL5693185 | 0.84 | CHEK1 (0.56) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL27691457 | 0.84 | CHEK1 (0.53) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL5693180 | 0.84 | CHEK1 (0.56) | CHEK1KDRCDK4FGFR1TTK | |
| SCHEMBL18688554 | 0.84 | KDR (0.57) | CHEK1KDRCDK4FGFR1TTK | |
| Hydrochloric Acid SCHEMBL5693182 | 0.83 | KDR (0.52) | KDM4EGAACHEK1KDRCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689358-B2 | Method for producing indazole compound, and indazole compound | FUJIFILM CORPORATION (JP) | 2020-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689358-B2 | Method for producing indazole compound, and indazole compound | CYP3A5, NAT1, CYP3A43 | MAPT 3728/4885KDM4E 3705/4885MEN1 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.