Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 9/20 | 0.41 |
| ▸ | NPY1R | P25929 | 8/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.41 |
| ▸ | NPY2R | P49146 | 6/20 | 0.41 |
| ▸ | NMT2 | O60551 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342260 | 0.99 | TLR2 (0.43) | TLR2SIRT6SIRT1ROCK2PRKACA | |
| SCHEMBL31593243 | 0.92 | SLC15A2 (0.43) | TLR2SIRT6SIRT1ROCK2NPY4R | |
| SCHEMBL29516817 | 0.91 | TLR2 (0.48) | TLR2SIRT6SIRT1ROCK2PRKACA | |
| SCHEMBL22341243 | 0.91 | SIRT6 (0.44) | TLR2SIRT6SIRT1ROCK2PRKACA | |
| SCHEMBL17930107 | 0.90 | SLC15A2 (0.47) | TLR2SIRT6SIRT1ROCK2NPY4R | |
| SCHEMBL30758138 | 0.89 | NPY4R (0.45) | TLR2SIRT6SIRT1NPY4RNPY1R | |
| SCHEMBL30819414 | 0.88 | GNAI3 (0.46) | TLR2NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31589116 | 0.88 | NMT1 (0.41) | TLR2SIRT6SIRT1ROCK2NPY4R | |
| SCHEMBL15358627 | 0.87 | TLR2 (0.40) | TLR2SIRT6SIRT1ROCK2PRKACA | |
| SCHEMBL12015094 | 0.87 | QRFPR (0.40) | NPY4RNPY1RNPY5RNPY2RQRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |