Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14070022 | 0.84 | LMNA (0.64) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL29624374 | 0.79 | HPGD (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL583659 | 0.79 | HPGD (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL4134378 | 0.75 | LMNA (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL31448388 | 0.75 | HPGD (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL1464773 | 0.75 | HPGD (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL29447932 | 0.75 | HPGD (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL895213 | 0.75 | HPGD (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL2890802 | 0.75 | HPGD (0.59) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL4594814 | 0.75 | LMNA (0.59) | LMNAHPGDALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020129082-A1 | COMPOUNDS FOR THE INHIBITION OF UNREGULATED CELL GROWTH | GODAVARI BIOREFINERIES LIMITED (IN) | 2020-06-25 | — | — | WO | disclosed |