Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206539 | 0.86 | ADRA1A (0.57) | ADRA1AFOLH1PLA2G10SIRT5PLA2G2C | |
| SCHEMBL24486692 | 0.82 | PLA2G2C (0.42) | FOLH1PLA2G10PLA2G2CCTSK | |
| SCHEMBL173035 | 0.82 | PLA2G2C (0.42) | FOLH1PLA2G10PLA2G2CCTSK | |
| SCHEMBL17813082 | 0.81 | PLA2G2C (0.46) | PLA2G10PLA2G2CMAPK1MEN1KMT2A | |
| SCHEMBL12295242 | 0.79 | PLA2G2C (0.44) | ADRA1APLA2G10PLA2G2CMAPK1EPHX2 | |
| SCHEMBL20380824 | 0.79 | FOLH1 (0.58) | ADRA1AFOLH1SIRT5EPHX2 | |
| SCHEMBL14240724 | 0.79 | PLA2G2C (0.44) | ADRA1APLA2G10PLA2G2CMAPK1EPHX2 | |
| SCHEMBL12664911 | 0.78 | PLA2G2C (0.49) | FOLH1PLA2G10PLA2G2CMAPK1MEN1 | |
| SCHEMBL25666774 | 0.77 | PLA2G2C (0.53) | PLA2G10PLA2G2CMAPK1MEN1KMT2A | |
| SCHEMBL17793312 | 0.77 | EPHX2 (0.50) | ADRA1APLA2G10KDM4EMAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127796-A2 | POLYPEPTIDES HAVING PEPTIDOGLYCAN DEGRADING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES A/S (DK) | 2020-06-25 | — | — | WO | disclosed |