Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170084 | 0.91 | RAB9A (0.42) | PIK3CDEPHX1RAB9ANPC1HTR4 | |
| SCHEMBL22135056 | 0.85 | EPHX1 (0.38) | EPHX1RAB9AEPHX2GAAKDM4E | |
| SCHEMBL16890334 | 0.80 | EPHX1 (0.45) | NAMPTEPHX1RAB9ANPC1EPHX2 | |
| SCHEMBL29306397 | 0.77 | HSD17B10 (0.48) | PIK3CDEPHX2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11168376 | 0.77 | EPHX1 (0.53) | EPHX1EPHX2GAAKDM4ESMN1; SMN2 | |
| SCHEMBL20666095 | 0.76 | HTT (0.43) | PIK3CDEPHX1RAB9ANPC1HTR4 | |
| SCHEMBL22135151 | 0.76 | KDM4E (0.40) | PIK3CDRAB9ANPC1GAAKDM4E | |
| SCHEMBL13853551 | 0.74 | NPC1 (0.42) | NAMPTEPHX1RAB9ANPC1EPHX2 | |
| SCHEMBL12764359 | 0.73 | NPC1 (0.39) | NAMPTPIK3CDRAB9ANPC1HTR4 | |
| SCHEMBL23848111 | 0.73 | EPHX1 (0.46) | EPHX1RAB9ANPC1EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |