Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136296 | 0.86 | PRSS1 (0.46) | MAPTKDM4EALDH1A1PRSS1LMNA | |
| SCHEMBL22135368 | 0.80 | ADORA2A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1KMT2A | |
| SCHEMBL22428322 | 0.74 | PRSS1 (0.71) | MAPTHSD17B10GAAKDM4EALDH1A1 | |
| SCHEMBL29513036 | 0.74 | PRSS1 (0.71) | MAPTHSD17B10GAAKDM4EALDH1A1 | |
| SCHEMBL22134963 | 0.73 | HPGD (0.62) | MAPTHSD17B10KDM4EKMT2ALMNA | |
| SCHEMBL22135376 | 0.73 | MAPT (0.52) | MTNR1AMTNR1BMAPTHSD17B10GAA | |
| SCHEMBL31494211 | 0.73 | GAA (0.74) | MAPTHSD17B10GAAKDM4EALDH1A1 | |
| SCHEMBL29868630 | 0.73 | STING1 (0.51) | MAPTHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL29868198 | 0.72 | HPGD (0.67) | MAPTHSD17B10GAAKDM4EKMT2A | |
| SCHEMBL7874916 | 0.72 | MAPT (0.55) | MTNR1AMTNR1BMAPTHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |