Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135367 | 0.86 | MTNR1A (0.45) | PRSS1SMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL29513036 | 0.79 | PRSS1 (0.71) | PRSS1KDM4EHTTALDH1A1MAPT | |
| SCHEMBL22428322 | 0.79 | PRSS1 (0.71) | PRSS1KDM4EHTTALDH1A1MAPT | |
| SCHEMBL29512975 | 0.76 | PRSS1 (0.71) | PRSS1KDM4EHTTALDH1A1MAPT | |
| SCHEMBL22908881 | 0.76 | PRSS1 (0.71) | PRSS1KDM4EHTTALDH1A1MAPT | |
| SCHEMBL22136293 | 0.75 | CXCR4 (0.53) | EGLN3TDP1 | |
| SCHEMBL22908891 | 0.73 | PRSS1 (0.69) | PRSS1KDM4EHTTALDH1A1MAPT | |
| SCHEMBL2841675 | 0.73 | EGLN3 (0.61) | EGLN3TDP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5093875 | 0.73 | MAPK8 (0.48) | EGLN3 | |
| SCHEMBL4558106 | 0.72 | EGLN3 (0.64) | EGLN3TDP1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |