SCHEMBL22136113

SCHEMBL22136113

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cc(-c5ccc6ccc7cccnc7c6c5)cc5c4sc4ccccc45)cc3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.37
LMNA P02545 4/20 0.35
MAPT P10636 4/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GMNN O75496 1/20 0.34
TP53 P04637 1/20 0.34
HSP90AA1 P07900 1/20 0.34
MMP2 P08253 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MMP9 P14780 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
MMP8 P22894 1/20 0.34
CCR1 P32246 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22136064 0.96 LIMK1 (0.37) LIMK1LMNAMAPTKDM4ESMN1; SMN2
SCHEMBL22136098 0.95 ALOX5 (0.37) LIMK1LMNAMAPTKDM4ESMN1; SMN2
SCHEMBL22135984 0.95 LIMK1 (0.38) LIMK1LMNAMAPTKDM4ESMN1; SMN2
SCHEMBL22136115 0.90 TOP1 (0.36) LIMK1LMNAMAPTKDM4ETP53
SCHEMBL22136336 0.88 ALDH1A1 (0.39) LIMK1LMNAMAPTKDM4ECCR1
SCHEMBL22136058 0.87 CYP3A4 (0.41) LIMK1LMNAMAPTKDM4ESMN1; SMN2
SCHEMBL22136114 0.85 CYP11B1 (0.34) LIMK1LMNAMAPTKDM4ECCR1
SCHEMBL23331707 0.84 LIMK1 (0.36) LIMK1MAPTCCR1CCR8TOP1
SCHEMBL22135976 0.83 ALDH1A1 (0.38) LIMK1LMNAMAPTKDM4ECCR1
SCHEMBL21622807 0.82 ALOX5 (0.47) LIMK1LMNAMAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020130553-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 두산솔루스 주식회사 2020-06-25 WO disclosed