SCHEMBL22136242

SCHEMBL22136242

CCCn1c(NC(O)c2oc(C)nc2C)nc2cc(C(N)=O)cc(OCCCN3CCOCC3)c21

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22135896 0.89 STING1 (0.58) STING1
SCHEMBL22136278 0.87 STING1 (0.62) STING1
SCHEMBL22135903 0.85 STING1 (0.46) STING1
SCHEMBL22135914 0.84 STING1 (0.56) STING1
SCHEMBL22151663 0.83 STING1 (0.57) STING1
SCHEMBL22135968 0.80 STING1 (0.42) STING1
SCHEMBL21789961 0.77 STING1 (0.86) STING1
SCHEMBL23637130 0.77 STING1 (0.60) STING1
SCHEMBL22135898 0.76 STING1 (0.54) STING1
SCHEMBL22136286 0.74 STING1 (0.69) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132549-A1 STING HETEROCYCLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed