Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26940381 | 0.78 | KDM4E (0.42) | POLBGSK3AGSK3BALDH1A1KDM4E | |
| SCHEMBL27506471 | 0.77 | POLB (0.39) | POLBGSK3AGSK3BALDH1A1KDM4E | |
| SCHEMBL28744250 | 0.77 | ADORA2B (0.41) | ALDH1A1KDM4EADORA2B | |
| SCHEMBL3591122 | 0.75 | APEX1 (0.44) | POLBALDH1A1KDM4ELMNAADORA2B | |
| SCHEMBL291488 | 0.70 | — | — | |
| SCHEMBL3875250 | 0.70 | ALDH1A1 (0.59) | POLBALDH1A1KDM4ELMNAGAA | |
| SCHEMBL3576407 | 0.69 | POLB (0.46) | POLBALDH1A1KDM4ELMNAADORA2B | |
| SCHEMBL4768929 | 0.68 | POLB (0.59) | POLBALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11715139 | 0.67 | ADORA2A (0.36) | GSK3AGSK3BALDH1A1KDM4ELMNA | |
| SCHEMBL21911678 | 0.67 | ALDH1A1 (0.39) | POLBGSK3AGSK3BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |