Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 7/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135941 | 0.87 | MAP3K7 (0.53) | KDM4EKMT2AMEN1TSHRHTT | |
| SCHEMBL22135908 | 0.87 | STING1 (0.56) | KDM4EKMT2AMEN1TSHRHTT | |
| SCHEMBL22136298 | 0.80 | RAB9A (0.45) | KDM4EKMT2AMEN1TSHRHTT | |
| SCHEMBL22135940 | 0.78 | STING1 (0.47) | KDM4EKMT2AMEN1HTTPKM | |
| SCHEMBL22136253 | 0.78 | STING1 (0.50) | KDM4EKMT2AMEN1HTTPKM | |
| SCHEMBL23566409 | 0.77 | KDM4E (0.80) | KDM4EKMT2AMEN1TSHRHTT | |
| SCHEMBL22136290 | 0.75 | STING1 (0.43) | KDM4EKMT2AMEN1HTTPKM | |
| SCHEMBL22136237 | 0.75 | STING1 (0.58) | — | |
| SCHEMBL23566386 | 0.73 | KDM4E (0.78) | KDM4EKMT2AMEN1TSHRHTT | |
| SCHEMBL22135943 | 0.72 | STING1 (0.49) | KMT2AMEN1HTTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |