SCHEMBL22136392

SCHEMBL22136392

Brc1ccc2c3ccc4cc5ccccc5c5c6ccccc6n(c2c1)c3c45

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.37
ERBB2 P04626 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
AHR P35869 1/20 0.37
CYP2A6 P11509 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
CAMK2B Q13554 1/20 0.33
CAMK2G Q13555 1/20 0.33
CAMK2D Q13557 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
NQO2 P16083 2/20 0.31
NQO1 P15559 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22109881 0.85 CYP1A2 (0.40) ACHEERBB2CYP1A2FYNMAOA
SCHEMBL30388832 0.79 MEN1 (0.41) ACHECYP1A2CYP2A6MEN1KMT2A
SCHEMBL868330 0.79 MEN1 (0.41) ACHECYP1A2CYP2A6MEN1KMT2A
SCHEMBL29783004 0.79 MEN1 (0.41) ACHECYP1A2CYP2A6MEN1KMT2A
SCHEMBL20071437 0.78 CYP2A6 (0.37) ACHEERBB2CYP1A2FYNMAOA
SCHEMBL22109813 0.78 CYP1A2 (0.39) ACHEERBB2CYP1A2FYNMAOA
SCHEMBL22136390 0.77 ALKBH5 (0.34) ACHEERBB2CYP1A2FYNMAOA
SCHEMBL19890651 0.75 CYP2A6 (0.42) ACHEERBB2CYP1A2FYNMAOA
SCHEMBL22109700 0.75 CYP1A2 (0.36) ACHEERBB2CYP1A2FYNMAOA
SCHEMBL26522423 0.75 TSPO (0.38) ACHECYP1A2CYP2A6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020130378-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-06-25 WO disclosed