Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.37 |
| ▸ | TDO2 | P48775 | 11/20 | 0.36 |
| ▸ | IDO1 | P14902 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15836092 | 0.81 | TDO2 (0.38) | ROCK2TDO2IDO1NPC1MAPT | |
| SCHEMBL15835990 | 0.81 | TDO2 (0.38) | ROCK2TDO2IDO1NPC1MAPT | |
| SCHEMBL25497629 | 0.80 | CDK4 (0.41) | KDM4E | |
| SCHEMBL11885001 | 0.80 | IDO1 (0.46) | ROCK2TDO2IDO1 | |
| SCHEMBL10123835 | 0.80 | AHR (0.41) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL15631616 | 0.79 | CHUK (0.47) | ROCK2TDO2IDO1NPC1ALDH1A1 | |
| SCHEMBL17490042 | 0.79 | NPC1 (0.59) | TDO2IDO1NPC1MAPTKDM4E | |
| SCHEMBL24056889 | 0.79 | AHR (0.55) | ROCK2TDO2IDO1NPC1KDM4E | |
| SCHEMBL13509559 | 0.79 | TDO2 (0.49) | ROCK2TDO2IDO1NPC1MAPT | |
| SCHEMBL25494825 | 0.77 | KDM4E (0.32) | MAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-B1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2020-06-24 | — | — | EP | disclosed |