SCHEMBL10123835

SCHEMBL10123835

Bc1ccc2oc3ccc(B)cc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.41
MAPT P10636 7/20 0.41
SMN1; SMN2 Q16637 6/20 0.41
NPC1 O15118 5/20 0.41
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 5/20 0.41
RAB9A P51151 4/20 0.41
HPGD P15428 4/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
GFER P55789 1/20 0.38
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
HSD17B10 Q99714 2/20 0.33
MAOA P21397 2/20 0.33
PIM1 P11309 1/20 0.33
CSNK2A1 P68400 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15369305 0.89 MAPT (0.59) AHRMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL12675062 0.87 PIM1 (0.46) AHRMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL24662727 0.85 MAPT (0.55) AHRMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL16067916 0.83 KDM4E (0.40) AHRMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL21890581 0.83 MAPT (0.53) AHRMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL15889119 0.82 MAPT (0.52) AHRMAPTSMN1; SMN2NPC1KDM4E
SCHEMBL23505207 0.82 PLA2G2A (0.49) MAPTSMN1; SMN2NPC1KDM4EALDH1A1
SCHEMBL23204096 0.82 AHR (0.61) AHRALDH1A1KMT2ALMNA
SCHEMBL22138665 0.80 ROCK2 (0.37) MAPTSMN1; SMN2NPC1KDM4EALDH1A1
SCHEMBL24662751 0.80 MAPT (0.46) AHRMAPTSMN1; SMN2NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460866-A2 Organic electroluminescent element, display device and lighting device Konica Minolta Holdings, Inc. (JP) 2012-06-06 EP disclosed
EP-1344788-B1 Conjugated polymer comprising dibenzothiophene- or dibenzofuran-units and their use in polymer LEDs SUMITOMO CHEMICAL CO (JP) 2010-06-23 EP disclosed
WO-2009142870-A1 COMPOUND COMPRISING PHENYL PYRIDINE UNITS GENERAL ELECTRIC COMPANY (US) 2009-11-26 WO disclosed
WO-2009142867-A1 COMPOUND COMPRISING PHENYL PYRIDINE UNITS GENERAL ELECTRIC COMPANY (US) 2009-11-26 WO disclosed