Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL22124893 | 0.98 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2AMEN1USP2 | |
| SCHEMBL22144246 | 0.85 | KDM4E (0.45) | ALDH1A1KDM4EKMT2AMEN1USP2 | |
| SCHEMBL22124909 | 0.84 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AMEN1USP2 | |
| SCHEMBL22144125 | 0.83 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AMEN1USP2 | |
| SCHEMBL22144244 | 0.82 | KDM4E (0.36) | ALDH1A1KDM4EKMT2AMEN1USP2 | |
| SCHEMBL22144121 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EKMT2AMEN1HSD17B10 | |
| SCHEMBL22144122 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AMEN1USP2 | |
| SCHEMBL22124480 | 0.80 | RXFP1 (0.40) | ALDH1A1KDM4EKMT2AMEN1APOBEC3A | |
| SCHEMBL22144087 | 0.77 | NR4A2 (0.37) | ALDH1A1KDM4EKMT2AMEN1HSD17B10 | |
| SCHEMBL22144095 | 0.71 | MAPT (0.37) | ALDH1A1KDM4ERXFP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127168-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |