Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144125 | 0.92 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL22144249 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| Bromide SCHEMBL22124893 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL22124424 | 0.83 | MAPT (0.37) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL22144102 | 0.77 | PRNP (0.42) | KDM4ESMN1; SMN2ALOX15MAPK1RXFP1 | |
| SCHEMBL22144116 | 0.74 | KDM4E (0.32) | KDM4EALDH1A1HPGDRXFP1CYP1A2 | |
| SCHEMBL22144244 | 0.74 | KDM4E (0.36) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL22124909 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL22144248 | 0.73 | NCF1 (0.36) | ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL28629290 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGDMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127168-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |