Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 2/20 | 0.68 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942476 | 0.92 | PDE4A (0.60) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL1941945 | 0.92 | PDE4A (0.60) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL1942645 | 0.89 | WHR1 (0.54) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL6779398 | 0.88 | PDE4A (0.56) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL1942139 | 0.88 | PDE4A (0.56) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL1943249 | 0.87 | PDE4A (0.55) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL1941528 | 0.87 | PDE4A (0.55) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL6774540 | 0.87 | PDE4A (0.55) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL6774543 | 0.87 | PDE4A (0.55) | WHR1NUDT1PDE4APDE4BPDE4C | |
| SCHEMBL16502036 | 0.87 | PDE4A (0.69) | WHR1NUDT1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542240-B2 | STK19 inhibitors for treatment of cancer | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-01-03 | — | — | US | disclosed |
| US-20200199081-A1 | STK19 INHIBITORS FOR TREATMENT OF CANCER | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-06-25 | — | — | US | disclosed |
| WO-2020132409-A1 | STK19 INHIBITORS FOR TREATMENT OF CANCER | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199081-A1 | STK19 INHIBITORS FOR TREATMENT OF CANCER | STK11, CDK9, STK3 | WHR1 2741/4885NUDT1 3938/4885PDE4A 3410/4885 |
| US-11542240-B2 | STK19 inhibitors for treatment of cancer | STK11, CDK9, STK3 | WHR1 2741/4885NUDT1 3938/4885PDE4A 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.