Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268381 | 0.80 | CRBN (0.70) | GLADDB1CRBNFFAR1HTT | |
| SCHEMBL27429818 | 0.77 | GSK3B (0.49) | GSK3BDDB1CRBNCHRNA7CHRNB2 | |
| Bicarbonate SCHEMBL29264497 | 0.76 | CRBN (0.64) | GLADDB1CRBNFFAR1HTT | |
| SCHEMBL8931319 | 0.75 | GSK3B (0.47) | GSK3BDDB1CRBNCHRNA7CHRNB2 | |
| SCHEMBL30526504 | 0.73 | FFAR1 (0.56) | GSK3BGLADDB1CRBNFFAR1 | |
| SCHEMBL29049422 | 0.73 | FFAR1 (0.56) | GSK3BGLADDB1CRBNFFAR1 | |
| SCHEMBL31139945 | 0.71 | GLA (0.60) | GSK3BGLADDB1CRBNFFAR1 | |
| SCHEMBL11627271 | 0.71 | GLA (0.64) | GLADDB1CRBNFFAR1HTT | |
| SCHEMBL11270285 | 0.71 | GLA (0.60) | GSK3BGLADDB1CRBNLMNA | |
| SCHEMBL5767796 | 0.71 | GLA (0.60) | GLADDB1CRBNLMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |