Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146663 | 0.97 | ALOX5 (0.44) | ALOX5PDK2MAPTKDM4EMEN1 | |
| SCHEMBL328681 | 0.89 | ALOX5 (0.51) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL437557 | 0.89 | ALOX5 (0.51) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL18086197 | 0.88 | ALOX5 (0.54) | ALOX5PDK2MAPTKDM4EMEN1 | |
| SCHEMBL437565 | 0.88 | ALOX5 (0.50) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL371197 | 0.87 | ALOX5 (0.54) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL440707 | 0.86 | ALOX5 (0.50) | ALOX5PDK2MAPTKDM4EMEN1 | |
| SCHEMBL16182152 | 0.86 | ALOX5 (0.52) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL438766 | 0.86 | ALOX5 (0.52) | ALOX5MAPTKDM4EMEN1LMNA | |
| SCHEMBL17692383 | 0.85 | ALOX5 (0.51) | ALOX5PDK2MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| WO-2020127259-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | ALOX5 3331/4885PDK2 519/4885MAPT 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.