Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 4/20 | 0.57 |
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 4/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979788 | 0.88 | CHEK1 (0.47) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL2215993 | 0.86 | CHEK1 (0.53) | CHEK1ACHEMAPTPIM1PDPK1 | |
| SCHEMBL12666733 | 0.85 | CHEK1 (0.69) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL2216558 | 0.82 | CHEK1 (0.54) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL1559867 | 0.81 | CHEK1 (0.51) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL1561400 | 0.81 | CHEK1 (0.60) | CHEK1ACHEMAPTPIM1ALK | |
| SCHEMBL1559826 | 0.79 | PIM1 (0.43) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL1979638 | 0.77 | PIM1 (0.44) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL473684 | 0.74 | CHEK1 (0.58) | CHEK1ACHEMAPTPIM1 | |
| SCHEMBL12666721 | 0.73 | CHEK1 (0.56) | CHEK1ACHEMAPTPIM1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | US | claimed |
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178053-A1 | AZACARBOLINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | AOC3, CBR3, IDH3B | CHEK1 786/4885ACHE 4362/4885MAPT 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.