SCHEMBL2214760

SCHEMBL2214760

CC(O)CSC(O)CSC(O)CSCCO

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.36
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2216461 0.88 ROCK2 (0.32) ROCK2TDP1
SCHEMBL710785 0.82
SCHEMBL5316674 0.80 TDP1 (0.45) ROCK2TDP1
SCHEMBL2218380 0.79 TDP1 (0.36) ROCK2TDP1
SCHEMBL1148911 0.69
SCHEMBL13965469 0.69 TDP1 (0.50) ROCK2TDP1
Thiodiglycol SCHEMBL11578815 0.69 TDP1 (0.59) ROCK2TDP1
SCHEMBL2058553 0.69 TSHR (0.39) TDP1
SCHEMBL11309790 0.69 ROCK2 (0.45) ROCK2TDP1
SCHEMBL16212597 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2008998-B1 PROCESS FOR PRODUCTION OF (POLY)THIOL COMPOUND FOR USE AS OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2013-06-05 EP disclosed
US-20110178264-A1 PROCESS FOR PRODUCING (POLY)THIOL COMPOUND FOR USE AS OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND MITSUI CHEMICALS, INC. (JP) 2011-07-21 US disclosed
US-20100298521-A1 PROCESS FOR PRODUCING (POLY)THIOL COMPOUND FOR USE AS OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND MITSUI CHEMICALS, INC. (JP) 2010-11-25 US disclosed
US-20090264613-A1 PROCESS FOR PRODUCING (POLY)THIOL COMPOUND FOR USE AS OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND MITSUI CHEMICALS, INC. (JP) 2009-10-22 US disclosed
EP-1524289-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-16 EP disclosed
EP-2008998-A1 PROCESS FOR PRODUCTION OF (POLY)THIOL COMPOUND FOR USE AS OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND Mitsui Chemicals, Inc. (JP) 2008-12-31 EP disclosed
US-20070149639-A1 Polymerizable composition, optical material comprising the composition and method for producing the material HORIKOSHI HIROSHI 2007-06-28 US disclosed
EP-1524289-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-04-20 EP disclosed
US-20040254258-A1 Polymerizable composition, optical material comprising the composition and method for producing the material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2004-12-16 US disclosed