Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | DHFR | P00374 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ALB | P02768 | 1/20 | 0.70 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | EIF4E | P06730 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652620 | 0.88 | TTR (0.66) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| Diflunisal SCHEMBL4337 | 0.83 | ACMSD (1.00) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| Diflunisal SCHEMBL30509654 | 0.83 | ACMSD (1.00) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| SCHEMBL18096517 | 0.83 | TTR (0.72) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| Diflunisal SCHEMBL3848363 | 0.83 | ACMSD (1.00) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| Diflunisal SCHEMBL29367380 | 0.83 | ACMSD (1.00) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| SCHEMBL3143118 | 0.82 | ALDH1A1 (0.49) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| SCHEMBL505466 | 0.82 | TTR (0.71) | TTRALDH1A1ACMSDKDM4EMEN1 | |
| SCHEMBL3128937 | 0.82 | GRIK1 (0.55) | ALDH1A1ACMSDKDM4EMEN1DHFR | |
| Diflunisal SCHEMBL20876816 | 0.81 | ACMSD (0.97) | TTRALDH1A1ACMSDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020128529-A1 | COMPOSITIONS AND USES THEREOF | BENEVOLENTAI BIO LIMITED (GB) | 2020-06-25 | — | — | WO | disclosed |