SCHEMBL22149262

SCHEMBL22149262

O=C(O)c1c(O)cc(CCc2ccccc2)cc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
SLC5A1 P13866 1/20 0.56
SLC5A2 P31639 1/20 0.56
DAO P14920 3/20 0.51
BID P55957 1/20 0.51
BCL2L1 Q07817 1/20 0.51
MCL1 Q07820 1/20 0.51
BAK1 Q16611 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CBS P35520 1/20 0.50
P2RX3 P56373 1/20 0.49
IGF1R P08069 1/20 0.48
ALOX15 P16050 1/20 0.48
FFAR1 O14842 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19420275 0.86 SLC5A1 (0.56) GAAMAPTSLC5A1SLC5A2CA12
SCHEMBL29057706 0.80 PTPN1 (0.63) GAAMAPTSLC5A1SLC5A2BID
SCHEMBL716420 0.79 IGF1R (0.55) DAOBCL2L1MCL1IGF1RALOX15
SCHEMBL22149143 0.77 SOX18 (0.48) BIDBCL2L1MCL1BAK1CA12
SCHEMBL29196805 0.76 MEN1 (0.67) SLC5A1SLC5A2MCL1HDAC6
SCHEMBL21530605 0.76 BID (0.79) MAPTBIDBCL2L1MCL1BAK1
SCHEMBL11381562 0.75 FFAR1 (0.52) MAPTDAOBIDBCL2L1MCL1
SCHEMBL27766830 0.75 GAA (0.59) GAADAOFFAR1HDAC1KEAP1
Stilbostemin B SCHEMBL31039665 0.75 IGF1R (0.52) GAAMAPTSLC5A1SLC5A2DAO
SCHEMBL9253391 0.74 BID (0.54) BIDBCL2L1MCL1BAK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11058619-B2 Carboxylated polyphenol derivatives and their cosmetic use L'ORÉAL (FR) 2021-07-13 US disclosed
US-20200197275-A1 CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE L'OREAL (FR) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200197275-A1 CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE H1-0, GLA, NQO1 GAA 827/4885MAPT 1170/4885SLC5A1 4088/4885
US-11058619-B2 Carboxylated polyphenol derivatives and their cosmetic use H1-0, GLA, NQO1 GAA 827/4885MAPT 1170/4885SLC5A1 4088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.