⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384637 | 0.88 | ALDH1A1 (0.37) | — | |
| SCHEMBL16135279 | 0.84 | TDP1 (0.46) | — | |
| SCHEMBL6762459 | 0.78 | — | — | |
| SCHEMBL10894191 | 0.78 | — | — | |
| SCHEMBL6158336 | 0.78 | — | — | |
| SCHEMBL7172295 | 0.78 | MAOA (0.42) | — | |
| SCHEMBL9319 | 0.77 | — | — | |
| SCHEMBL27763265 | 0.76 | — | — | |
| Hydrogen Sulfide SCHEMBL29094904 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27996106 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600797-A | Composition comprising tetrahydrocannabinol for the treatment of acute respiratory failure and/or acute respiratory distress syndrome | A·N·纳吉 | 2023-08-15 | — | — | CN | disclosed |
| US-8895558-B2 | Arylpiperazine-containing pyrrole 3-carboxamide derivatives for treating depressive disorders | GREEN CROSS CORPORATION (KR) | 2014-11-25 | — | — | US | disclosed |
| US-20110178091-A1 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2011-07-21 | — | — | US | disclosed |
| WO-2010038948-A2 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2010-04-08 | — | — | WO | disclosed |