Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342612 | 1.00 | PRCP (0.37) | PRCPFPR2ITGB3ITGA2BKMT2A | |
| SCHEMBL16342611 | 1.00 | PRCP (0.37) | PRCPFPR2ITGB3ITGA2BKMT2A | |
| SCHEMBL17825459 | 1.00 | PRCP (0.37) | PRCPFPR2ITGB3ITGA2BKMT2A | |
| SCHEMBL16295882 | 0.94 | PYGL (0.38) | PRCPFPR2ITGB3ITGA2BACE2 | |
| SCHEMBL16343488 | 0.94 | PYGL (0.38) | PRCPFPR2ITGB3ITGA2BACE2 | |
| SCHEMBL16306082 | 0.93 | PRCP (0.42) | PRCPFPR2KMT2AACKR3F10 | |
| SCHEMBL16306070 | 0.92 | F10 (0.39) | PRCPFPR2ITGB3ITGA2BKMT2A | |
| SCHEMBL28532158 | 0.92 | F10 (0.39) | PRCPFPR2ITGB3ITGA2BKMT2A | |
| SCHEMBL28532160 | 0.92 | F10 (0.39) | PRCPFPR2ITGB3ITGA2BKMT2A | |
| SCHEMBL17945643 | 0.92 | F10 (0.39) | PRCPFPR2ITGB3ITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074820-B | GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457301-A | Novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-03-09 | — | — | CN | disclosed |
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |