Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26574593 | 0.86 | PDK2 (0.44) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL22150986 | 0.85 | MEN1 (0.46) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL24328652 | 0.85 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL22799511 | 0.84 | PDK2 (0.40) | PDK2KDM4ESERPINE1MCL1ACMSD | |
| SCHEMBL29575912 | 0.83 | PDK2 (0.51) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL19850003 | 0.83 | PDK2 (0.51) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL17903070 | 0.82 | MCL1 (0.38) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL24329307 | 0.81 | CYP2A6 (0.44) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL22146802 | 0.81 | ALOX5 (0.45) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL22146693 | 0.81 | ALOX5 (0.45) | PDK2KDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127145-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |