Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 18/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889815 | 1.00 | FPR2 (0.70) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22622419 | 0.91 | FPR2 (0.73) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14889939 | 0.91 | FPR2 (0.73) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL22150325 | 0.86 | FPR2 (0.70) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14902575 | 0.86 | FPR2 (0.63) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL28352113 | 0.86 | FPR2 (0.63) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL23129928 | 0.85 | FPR2 (0.71) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14889720 | 0.85 | FPR2 (0.71) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL27981750 | 0.85 | FPR2 (0.71) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL20484373 | 0.84 | FPR2 (0.70) | FPR2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | claimed |
| CN-106518742-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2017-03-22 | — | — | CN | claimed |
| CN-104114164-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2016-11-16 | — | — | CN | claimed |
| CN-104114164-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | ALLERGAN INC | 2014-10-22 | — | — | CN | claimed |
| CN-106518742-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104114164-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104114164-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | ALLERGAN INC | 2014-10-22 | — | — | CN | disclosed |