SCHEMBL28352113

SCHEMBL28352113

CC(C)(C)OC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 15/20 0.63
CTSS P25774 4/20 0.54
CTSK P43235 3/20 0.54
CTSB P07858 2/20 0.52
CTSL P07711 1/20 0.52
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14902575 1.00 FPR2 (0.63) FPR2CTSSCTSKCTSBCTSL
SCHEMBL28348581 0.91 FPR2 (0.60) FPR2CTSSCTSKCTSBCTSL
SCHEMBL14889686 0.91 FPR2 (0.60) FPR2CTSSCTSKCTSBCTSL
SCHEMBL14902624 0.86 FPR2 (0.70) FPR2MEN1NPC1RAB9AKMT2A
SCHEMBL28348563 0.86 FPR2 (0.70) FPR2MEN1NPC1RAB9AKMT2A
SCHEMBL22150326 0.86 FPR2 (0.70) FPR2MEN1NPC1RAB9AKMT2A
SCHEMBL14889815 0.86 FPR2 (0.70) FPR2MEN1NPC1RAB9AKMT2A
SCHEMBL14889939 0.86 FPR2 (0.73) FPR2MEN1NPC1RAB9AKMT2A
SCHEMBL22622419 0.86 FPR2 (0.73) FPR2MEN1NPC1RAB9AKMT2A
SCHEMBL20484129 0.85 FPR2 (0.64) FPR2MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106518742-B Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators 阿勒根公司 2020-01-21 CN disclosed