Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150437 | 1.00 | LPL (0.38) | LPLLIPGROCK1AAK1 | |
| SCHEMBL22150454 | 0.85 | LPL (0.33) | LPLLIPGROCK1AAK1 | |
| SCHEMBL22150452 | 0.85 | LPL (0.33) | LPLLIPGROCK1AAK1 | |
| SCHEMBL22150465 | 0.85 | LPL (0.33) | LPLLIPGROCK1AAK1 | |
| SCHEMBL16334766 | 0.83 | LIPG (0.40) | LPLLIPGROCK1AAK1 | |
| SCHEMBL28467537 | 0.83 | LIPG (0.40) | LPLLIPGROCK1AAK1 | |
| SCHEMBL16334515 | 0.83 | LIPG (0.40) | LPLLIPGROCK1AAK1 | |
| SCHEMBL28457776 | 0.82 | ROCK1 (0.34) | LIPGROCK1 | |
| SCHEMBL28457778 | 0.82 | ROCK1 (0.34) | LIPGROCK1 | |
| SCHEMBL16334118 | 0.81 | ROCK1 (0.35) | LPLLIPGROCK1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013796-B9 | BIARYL DERIVATIVES AS GPR120 AGONISTS | LG CHEMICAL LTD (KR) | 2020-07-01 | — | — | EP | disclosed |