Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 5/20 | 0.68 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 13/20 | 0.68 |
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | GBA1 | P04062 | 9/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125141 | 0.88 | SMARCA2 (0.72) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22125195 | 0.82 | SMARCA2 (1.00) | SMARCA2SMARCA4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9599834 | 0.81 | SMARCA2 (0.86) | SMARCA2SMARCA4RAB9ANPC1MAPT | |
| SCHEMBL22125285 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11045048 | 0.81 | SMARCA2 (0.71) | SMARCA2SMARCA4RAB9ANPC1GBA1 | |
| SCHEMBL22125510 | 0.81 | SMARCA2 (0.81) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14353530 | 0.80 | RAB9A (1.00) | RAB9ANPC1GBA1SMN1; SMN2MAPT | |
| SCHEMBL22125520 | 0.78 | SMARCA2 (0.76) | SMARCA2SMARCA4MAPTMEN1KMT2A | |
| SCHEMBL9410880 | 0.77 | MEN1 (0.72) | SMARCA2SMARCA4RAB9ANPC1MAPT | |
| SCHEMBL11046021 | 0.77 | SMARCA2 (0.75) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |