Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.68 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GNG2 | P59768 | 1/20 | 0.44 |
| ▸ | GNB1 | P62873 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22155312 | 0.86 | SMARCA2 (0.66) | SMARCA2SMARCA4RAB9AMEN1KMT2A | |
| SCHEMBL22125259 | 0.86 | SMARCA2 (0.71) | SMARCA2SMARCA4RAB9AMEN1KMT2A | |
| SCHEMBL22125519 | 0.84 | SMARCA2 (0.69) | SMARCA2SMARCA4RAB9AMEN1KMT2A | |
| SCHEMBL9599834 | 0.83 | SMARCA2 (0.86) | SMARCA2SMARCA4RAB9AMEN1KMT2A | |
| SCHEMBL22154748 | 0.83 | SMARCA2 (0.68) | SMARCA2SMARCA4KDRRAB9AMEN1 | |
| SCHEMBL22155017 | 0.83 | SMARCA2 (0.62) | SMARCA2SMARCA4RAB9AMEN1KMT2A | |
| SCHEMBL11046021 | 0.82 | SMARCA2 (0.75) | SMARCA2SMARCA4KDRRAB9AMEN1 | |
| SCHEMBL22125195 | 0.81 | SMARCA2 (1.00) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL11594185 | 0.81 | MEN1 (0.58) | RAB9AMEN1KMT2ANPC1CNR1 | |
| SCHEMBL22155047 | 0.81 | SMARCA2 (0.68) | SMARCA2SMARCA4RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |