Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.62 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22155091 | 0.84 | SMARCA2 (0.64) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22154752 | 0.83 | SMARCA2 (0.68) | SMARCA2SMARCA4MEN1KMT2ANPC1 | |
| SCHEMBL9599834 | 0.83 | SMARCA2 (0.86) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22155312 | 0.83 | SMARCA2 (0.66) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22125317 | 0.80 | GRM4 (0.60) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22125514 | 0.80 | SMARCA2 (0.66) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22125257 | 0.80 | GRM4 (0.60) | SMARCA2SMARCA4MEN1KMT2AMAPT | |
| SCHEMBL29555847 | 0.80 | SMARCA2 (0.69) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL11047103 | 0.79 | SMARCA2 (0.79) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22154751 | 0.79 | SMARCA2 (0.64) | SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |