Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aluminum Chloride Anhydrous SCHEMBL27692479 | 0.95 | ALDH1A1 (0.51) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7731637 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7732675 | 0.94 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1573285 | 0.90 | ALDH1A1 (0.59) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28766884 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4657892 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1352270 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4659331 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27930026 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7732980 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369412-B1 | Process for the preparation of 5-nitro-3,4-dihydro-1(2H)-naphthalenone, 1,5-naphthalendiamine and 1,5-naphthalendiisocyanate | BAYER MATERIALSCIENCE AG (DE) | 2011-07-27 | — | — | EP | claimed |
| CN-100343225-C | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER AG (DE) | 2007-10-17 | — | — | CN | claimed |
| US-7202378-B2 | Process for producing 5-nitro-3,4-dihydro-1(H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER MATERIALSCIENCE AG (DE) | 2007-04-10 | — | — | US | claimed |
| US-7202384-B2 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER MATERIALSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-04-10 | — | — | US | claimed |
| US-20060183946-A1 | Process for producing 5-nitro-3,4-dihydro-1(H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | COVESTRO DEUTSCHLAND AG (DE) | 2006-08-17 | — | — | US | claimed |
| US-20060178526-A1 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | COVESTRO DEUTSCHLAND AG (DE) | 2006-08-10 | — | — | US | claimed |
| US-7057071-B2 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER MATERIALSCIENCE AG (DE) | 2006-06-06 | — | — | US | claimed |
| CN-1467195-A | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | — | 2004-01-14 | — | — | CN | claimed |
| US-20030229252-A1 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | COVESTRO DEUTSCHLAND AG (DE) | 2003-12-11 | — | — | US | claimed |
| CN-100343225-C | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER AG (DE) | 2007-10-17 | — | — | CN | disclosed |
| US-7202384-B2 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER MATERIALSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-04-10 | — | — | US | disclosed |
| US-7202378-B2 | Process for producing 5-nitro-3,4-dihydro-1(H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER MATERIALSCIENCE AG (DE) | 2007-04-10 | — | — | US | disclosed |
| US-20060183946-A1 | Process for producing 5-nitro-3,4-dihydro-1(H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | COVESTRO DEUTSCHLAND AG (DE) | 2006-08-17 | — | — | US | disclosed |
| US-20060178526-A1 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1,5-naphthalenediamine and 1,5-naphthalene diisocyanate | COVESTRO DEUTSCHLAND AG (DE) | 2006-08-10 | — | — | US | disclosed |
| US-7057071-B2 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | BAYER MATERIALSCIENCE AG (DE) | 2006-06-06 | — | — | US | disclosed |
| CN-1467195-A | Process for producing 5-nitro-3,4-dihydro-1(2h)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | — | 2004-01-14 | — | — | CN | disclosed |
| US-20030229252-A1 | Process for producing 5-nitro-3,4-dihydro-1(2H)-naphthalinone, 1-5-naphthalenediamine and 1,5-naphthalene diisocyanate | COVESTRO DEUTSCHLAND AG (DE) | 2003-12-11 | — | — | US | disclosed |
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |