Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383344 | 0.91 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL151684 | 0.91 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL4657892 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL1352270 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL7732980 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL27930026 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL2215516 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL11197670 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL159214 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDRAB9ANPC1 | |
| SCHEMBL28766884 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1275934-C | Process for the production of 1, 5-naphthalenediamine | BAYER AG (DE) | 2006-09-20 | — | — | CN | claimed |
| CN-1483017-A | Process for the production of 1, 5-naphthalenediamine | 拜尔公司 | 2004-03-17 | — | — | CN | claimed |
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | claimed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | claimed |
| EP-1622567-B1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK SHARP & DOHME (US) | 2013-07-24 | — | — | EP | disclosed |
| EP-1295864-B1 | PROCESS FOR PREPARATION OF 1,5-DIAMINONAPHTHALENES | MITSUI CHEMICALS POLYURETHANES (JP) | 2008-12-03 | — | — | EP | disclosed |
| CN-1275934-C | Process for the production of 1, 5-naphthalenediamine | BAYER AG (DE) | 2006-09-20 | — | — | CN | disclosed |
| CN-1275934-C | Process for the production of 1, 5-naphthalenediamine | BAYER AG (DE) | 2006-09-20 | — | — | CN | disclosed |
| US-6737548-B2 | REACTING AN ORTHO-ALKYLNITROBENZENE WITH VINYL COMPOUND IN PRESENCE OF A BASE TO PRODUCE AN INTERMEDIATE, CYCLIZING THE INTERMEDIATE TO FORM 5-NITRO-1-TETRALONE COMPOUND, THEN REACTING WITH AMINE TO PRODUCE DIAMINONAPHTHALENE COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 2004-05-18 | — | — | US | disclosed |
| CN-1483017-A | Process for the production of 1, 5-naphthalenediamine | 拜尔公司 | 2004-03-17 | — | — | CN | disclosed |
| CN-1483017-A | Process for the production of 1, 5-naphthalenediamine | 拜尔公司 | 2004-03-17 | — | — | CN | disclosed |
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| CN-1464874-A | Process for preparation of 1,5-diaminonaphthalenes | MITSUI CHEMICALS INC (JP) | 2003-12-31 | — | — | CN | disclosed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20030176722-A1 | Process for preparation of 1,5-diaminonaphthalenes | MITSUI CHEMICALS POLYURETHANES, INC. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1295864-A1 | PROCESS FOR PREPARATION OF 1,5-DIAMINONAPHTHALENES | Mitsui Chemicals, Inc. (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | disclosed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BBOX1, CYP4B1, NAT1 | ALDH1A1 455/4885TSHR 3810/4885HPGD 119/4885 |
| US-20030176722-A1 | Process for preparation of 1,5-diaminonaphthalenes | NOX5, NOX1, DPYD | ALDH1A1 159/4885TSHR 4208/4885HPGD 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.