SCHEMBL22155394

SCHEMBL22155394

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)oc3c(B5OC(C)(C)C(C)(C)O5)cccc34)cc21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.34
ALOX5 P09917 2/20 0.34
LPL P06858 2/20 0.33
LIPG Q9Y5X9 2/20 0.33
PDK2 Q15119 1/20 0.30
CSF1R P07333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29571958 0.92 ALOX5 (0.34) ALOX5LPLLIPGPDK2
SCHEMBL22156109 0.92 ALOX5 (0.34) ALOX5LPLLIPGPDK2
SCHEMBL17889183 0.88 ALOX5 (0.36) PRKDCALOX5LPLLIPGPDK2
SCHEMBL24287132 0.88 ALOX5 (0.32) PRKDCALOX5LPLLIPG
SCHEMBL19824329 0.87
SCHEMBL22155399 0.85 LIPG (0.34) PRKDCALOX5LPLLIPG
SCHEMBL22156120 0.85
SCHEMBL32667839 0.84 LIPG (0.47) PRKDCALOX5LPLLIPGCSF1R
SCHEMBL22708833 0.84 LIPG (0.47) PRKDCALOX5LPLLIPGCSF1R
SCHEMBL22135393 0.84 ALOX5 (0.39) PRKDCALOX5LPLLIPGCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220109116-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-04-07 US disclosed
WO-2020127176-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220109116-A1 MATERIALS FOR ELECTRONIC DEVICES EED, EPHA6, ERCC1 PRKDC 1570/4885ALOX5 3331/4885LPL 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.