SCHEMBL22155609

SCHEMBL22155609

c1cc2ccc3ccc(-c4ccc(-c5ccc6c(c5)c5ccccc5c5cc7c(cc65)oc5ccccc57)cc4)c4ccc(c1)c2c34

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.38
CYP1A2 P05177 3/20 0.38
MAOA P21397 2/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
ACHE P22303 1/20 0.38
ALDH1A1 P00352 3/20 0.37
HPGD P15428 3/20 0.37
THRB P10828 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HCRTR1 O43613 1/20 0.35
DUSP3 P51452 1/20 0.34
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22255959 0.96 AHR (0.39) AHRCYP1A2MAOAERBB2FYN
SCHEMBL27127621 0.92 AHR (0.41) AHRCYP1A2MAOAERBB2FYN
SCHEMBL22255942 0.91 PLA2G2A (0.39) AHRCYP1A2MAOAALDH1A1HPGD
SCHEMBL22155604 0.90 AHR (0.39) AHRCYP1A2MAOAALDH1A1HPGD
SCHEMBL22155171 0.89 AHR (0.37) AHRCYP1A2MAOAERBB2FYN
SCHEMBL23464227 0.89 AHR (0.39) AHRCYP1A2MAOAERBB2FYN
SCHEMBL22255985 0.89 AHR (0.38) AHRCYP1A2MAOAALDH1A1HPGD
SCHEMBL23109679 0.88 AHR (0.42) AHRCYP1A2MAOAERBB2FYN
SCHEMBL24363040 0.88 MEN1 (0.37) AHRCYP1A2MAOAALDH1A1HPGD
SCHEMBL22256098 0.88 PLA2G2A (0.40) AHRCYP1A2FYNALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11296282-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-04-05 US disclosed
US-20200203632-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11296282-B2 Organic compound and organic electroluminescence device using the same SLCO4C1, EML4, SLCO2A1 AHR 2487/4885CYP1A2 911/4885MAOA 368/4885
US-20200203632-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, EML4, SLCO2A1 AHR 2487/4885CYP1A2 911/4885MAOA 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.