Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | BCL6 | P41182 | 7/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123511 | 0.87 | PTK6 (0.41) | EGFRIGF1RPTK6CSF1RALK | |
| SCHEMBL24105197 | 0.87 | EGFR (0.35) | EGFRIGF1RBCL6PTK6CSF1R | |
| SCHEMBL30167900 | 0.87 | EGFR (0.35) | EGFRIGF1RBCL6PTK6CSF1R | |
| Trifluoroacetic Acid SCHEMBL22123848 | 0.84 | PTK6 (0.38) | EGFRIGF1RPTK6CSF1RALK | |
| Hydrochloric Acid SCHEMBL22123800 | 0.82 | IGF1R (0.33) | EGFRIGF1RAURKA | |
| SCHEMBL25443967 | 0.82 | CCNT1 (0.45) | ALKAURKA | |
| SCHEMBL24105046 | 0.82 | AURKA (0.35) | EGFRIGF1RAURKA | |
| SCHEMBL30167778 | 0.82 | AURKA (0.35) | EGFRIGF1RAURKA | |
| SCHEMBL22124749 | 0.82 | CDK2 (0.36) | IGF1RPTK6ALK | |
| SCHEMBL22123805 | 0.82 | SYK (0.34) | EGFRPTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126953-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |