SCHEMBL2215724

SCHEMBL2215724

C=C(CC(CS(=O)(=O)O)c1ccccc1)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 3/20 0.42
GABBR1 Q9UBS5 3/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
FNTA P49354 2/20 0.38
FNTB P49356 2/20 0.38
SRC P12931 1/20 0.38
CYP2C19 P33261 4/20 0.36
ALDH1A1 P00352 1/20 0.36
EPHX1 P07099 1/20 0.35
SLC6A3 Q01959 3/20 0.34
DRD3 P35462 2/20 0.34
LMNA P02545 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
EDNRB P24530 1/20 0.34
MAPK1 P28482 1/20 0.34
MC4R P32245 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17183647 0.80 GABBR2 (0.46) GABBR2GABBR1CYP1A2CYP2D6PKM
SCHEMBL4814840 0.78 SRC (0.47) GABBR2GABBR1CYP1A2CYP2D6PKM
SCHEMBL1859129 0.78 GABBR2 (0.52) GABBR2GABBR1CYP1A2CYP2D6PKM
SCHEMBL22201007 0.76 ATM (0.56) GABBR2GABBR1CYP1A2SMN1; SMN2NPSR1
SCHEMBL4601734 0.75 GABBR2 (0.69) GABBR2GABBR1CYP1A2CYP2D6PKM
SCHEMBL4816135 0.75 EPHX1 (0.44) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL27509017 0.73 GABBR2 (0.47) GABBR2GABBR1CYP1A2CYP2D6PKM
SCHEMBL10591291 0.72 TAAR1 (0.47) CYP2C19ALDH1A1
SCHEMBL6728558 0.72 CCR5 (0.50) GABBR2GABBR1CYP1A2CYP2D6PKM
SCHEMBL19717638 0.70 EPHX1 (0.58) GABBR2GABBR1CYP1A2CYP2D6PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107141409-B Preparation method of paper reinforcing agent 广东省造纸研究所 2021-05-18 CN claimed
US-9957397-B2 Fire resistant glazing unit PYROGUARD UK LIMITED (GB) 2018-05-01 US claimed
EP-2817151-B1 FIRE RESISTANT GLAZING UNIT PYROGUARD UK LTD (GB) 2017-08-16 EP claimed
US-7524599-B2 Toner compositions XEROX CORPORATION (US) 2009-04-28 US claimed
US-20070224532-A1 TONER COMPOSITIONS XEROX CORPORATION (US) 2007-09-27 US claimed
JP-59230629-A None JP disclosed
US-11720036-B2 Toner CANON KABUSHIKI KAISHA (JP) 2023-08-08 US disclosed
CN-112601790-B Zinc halide phthalocyanine pigment, coloring composition and color filter DIC株式会社 2023-05-09 CN disclosed
EP-3546491-B1 CARBOXYL-GROUP-CONTAINING COPOLYMER, AND METHOD FOR PRODUCING SAME NIPPON CATALYTIC CHEM IND (JP) 2022-07-06 EP disclosed
US-20210397106-A1 TONER CANON KABUSHIKI KAISHA (JP) 2021-12-23 US disclosed
US-11021557-B2 Carboxyl-group-containing copolymer, and method for producing same NIPPON SHOKUBAI CO., LTD. (JP) 2021-06-01 US disclosed
CN-107141409-B Preparation method of paper reinforcing agent 广东省造纸研究所 2021-05-18 CN disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
US-5039757-A Alkaline hofmann degradation with a hypohalogenite at high te-mperature over short period of time; paper strength agent, fl-occulant MITSUI TOATSU CHEMICALS, INC. (JP) 1991-08-13 US disclosed
EP-0377313-A2 Cationic acrylamide polymers, a process for manufacturing them, and their uses MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-11 EP disclosed
US-4725499-A COPOLYMER OF A 2-ACRYLAMIDO-2-PHENYLSULFONIC ACID; PIGMENT DISPERSANTS; MITSUI TOATSU CHEMICALS, INC. (JP) 1988-02-16 US disclosed
US-4701283-A FROM AN UNSATURATED NITRILE AND B-HYDROXYALKANESULFONIC ACID IN FUMING SULFURIC ACID MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-10-20 US disclosed
US-4659773-A COPOLYMERIZING EMULSION WITH A RADICAL POLYMERIZABLE UNSATURATED BOND MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-04-21 US disclosed
JP-S59230629-A PIGMENT DISPERSANT MITSUI TOATSU CHEM INC 1984-12-25 JP disclosed
EP-0112921-A1 PROCESS FOR PREPARING AMIDOALKANESULFONIC ACID DERIVATIVES MITSUI TOATSU CHEMICALS, Inc. (JP) 1984-07-11 EP disclosed