SCHEMBL2215780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31273314	0.85	NOTUM (0.45)	NOTUMUBE2NCASRKCNH2SRC
	SCHEMBL17887295	0.81	NOTUM (0.42)	NOTUMUBE2NCASRKCNH2NPC1
	SCHEMBL508718	0.79	RXRA (0.44)	NOTUMMAPTPOLB
	SCHEMBL28835086	0.79	UBE2N (0.46)	NOTUMUBE2NCASRKCNH2SRC
	SCHEMBL26970950	0.78	MAOA (0.41)	NOTUMCASRMAPT
	SCHEMBL15670374	0.78	NOTUM (0.42)	NOTUMNPC1MAPTRAB9APOLB
	SCHEMBL5904887	0.77	NOTUM (1.00)	NOTUMKCNH2MAPT
	SCHEMBL30999699	0.77	NPC1 (0.54)	NOTUMUBE2NCASRSRCBRAF
	SCHEMBL16322113	0.77	NOTUM (0.59)	NOTUMUBE2NKCNH2NPC1MAPT
	SCHEMBL12438819	0.77	NOTUM (0.59)	NOTUMUBE2NCASRNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.