SCHEMBL22158295

SCHEMBL22158295

CC(=O)Nc1cc(Br)ccc1-c1ccc(Br)cc1NC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
HTT P42858 1/20 0.54
HDAC1 Q13547 1/20 0.49
RAB9A P51151 4/20 0.48
NPC1 O15118 3/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 1/20 0.48
DYRK1A Q13627 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
GPR35 Q9HC97 3/20 0.44
RXFP1 Q9HBX9 1/20 0.44
KDM4E B2RXH2 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2325682 0.86 SMN1; SMN2 (0.57) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL1284518 0.86 ALDH1A1 (0.64) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL28724549 0.84 ALDH1A1 (0.62) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL3715354 0.84 ALDH1A1 (0.58) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL29572629 0.84 ALDH1A1 (0.62) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL28888391 0.83 ALDH1A1 (0.43) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL29897648 0.82 RAB9A (0.67) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL5271785 0.82 RAB9A (0.67) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL4808346 0.82 ALDH1A1 (0.56) ALDH1A1HTTHDAC1RAB9ANPC1
SCHEMBL17871105 0.81 ALDH1A1 (0.58) ALDH1A1HTTHDAC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124512-B2 Compound, display panel and display apparatus XIAMEN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2021-09-21 US disclosed
US-20200207767-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS XIAMEN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124512-B2 Compound, display panel and display apparatus NR2E3, NR2E1, CPNE4 ALDH1A1 983/4885HTT 3948/4885HDAC1 2401/4885
US-20200207767-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS NR2E3, NR2E1, CPNE4 ALDH1A1 983/4885HTT 3948/4885HDAC1 2401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.