Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28993638 | 0.91 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| Lithium Ion SCHEMBL28993605 | 0.91 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| SCHEMBL22159580 | 0.84 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| SCHEMBL9576057 | 0.82 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| SCHEMBL28407034 | 0.82 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| SCHEMBL28929367 | 0.81 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| SCHEMBL22159585 | 0.81 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| Water SCHEMBL9576110 | 0.81 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2HPGD | |
| SCHEMBL29850560 | 0.81 | POLB (0.36) | SMN1; SMN2HPGDKMT2AMEN1LMNA | |
| Lithium Ion SCHEMBL29022183 | 0.81 | POLB (0.36) | SMN1; SMN2HPGDKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118320087-A | Polymer composite hydrogel, preparation method thereof and tooth desensitizing material | 吉林大学第一医院 | 2024-07-12 | — | — | CN | claimed |
| CN-115233445-B | Method for visible light catalytic real silk antibacterial durable finishing | 浙江理工大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118255953-A | Fucoidin 3D printing hydrogel for multifunctional tissue engineering and preparation method and application thereof | 湖南中科要素生物科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-116236623-B | Space-time adjustable infectious osteochondral defect magnesium alloy composite hydrogel stent material and preparation method and application thereof | 南京市第一医院 | 2024-06-25 | — | — | CN | claimed |
| CN-118126267-A | Application of modified bioactive glass in preparation of multifunctional hydrogel | 江苏海洋大学 | 2024-06-04 | — | — | CN | claimed |
| CN-116392397-B | Photoresponse gingival retraction material and preparation method and application thereof | 四川大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118105541-A | DNA-silk fibroin composite hydrogel microsphere and preparation method thereof | 上海大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118078993-A | Application of hyaluronic acid/gelatin-based magnetic hydrogel in preparation of medicines for treating hepatic fibrosis | 南京工业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118027447-A | Hyaluronic acid/gelatin-based magnetic hydrogel and preparation method and application thereof | 南京工业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-118006539-A | Liver-specific biological ink, preparation method thereof and primary hepatocyte 3D biological printing model constructed based on same | 宁波长都生物科技有限责任公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023130754-A1 | GREEN SYNTHESIS METHOD FOR ANTIBACTERIAL SUPERPOROUS HYDROGEL, PRODUCT THEREOF, AND USE THEREOF IN DEGRADATION OF VARIOUS POLLUTANTS IN WASTEWATER TREATMENT | 杭州师范大学 | 2023-07-13 | — | — | WO | claimed |
| CN-116392397-A | Photoresponse gingival retraction material and preparation method and application thereof | 四川大学 | 2023-07-07 | — | — | CN | claimed |
| CN-115920118-B | Double-crosslinked fibrin gel, kit and application thereof | 浙江大学 | 2023-07-04 | — | — | CN | claimed |
| CN-116330644-A | Projection type photo-curing biological 3D printing method | 浙江大学 | 2023-06-27 | — | — | CN | claimed |
| CN-116271113-A | Multifunctional photo-curing sound guide gel and preparation method and application thereof | 四川大学华西医院 | 2023-06-23 | — | — | CN | claimed |
| CN-115671372-B | Raw material composition and method for preparing double-crosslinked fibrin adhesive | 浙江大学 | 2023-06-20 | — | — | CN | claimed |
| CN-116236623-A | Space-time adjustable infectious osteochondral defect magnesium alloy composite hydrogel stent material and preparation method and application thereof | 南京市第一医院 | 2023-06-09 | — | — | CN | claimed |
| CN-116175956-A | Preparation method of attachable tissue engineering scaffold material based on suspension printing technology | 北京大学 | 2023-05-30 | — | — | CN | claimed |
| CN-116059436-A | Precursor of gel-like curable strong-adhesion tissue adhesive, and preparation method and application method thereof | 北京化工大学 | 2023-05-05 | — | — | CN | claimed |
| CN-115028903-A | Hydrogel and preparation method and application thereof | 广州创赛生物医用材料有限公司 | 2022-09-09 | — | — | CN | claimed |