SCHEMBL2215967

SCHEMBL2215967

Cc1cc(OCCCC2CCN(c3noc(C(C)CN(C)C)n3)CC2)ccc1C(=O)NC[C@H](O)CO

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 6/20 0.36
ACACB O00763 3/20 0.35
ACACA Q13085 3/20 0.35
LNPEP Q9UIQ6 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
JAK2 O60674 3/20 0.32
NTRK1 P04629 3/20 0.32
SLC2A1 P11166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12434725 0.92 GPR119 (0.37) GPR119ACACBACACALNPEPRAB9A
SCHEMBL2372646 0.92 GPR119 (0.39) GPR119ACACBACACALNPEPRAB9A
SCHEMBL2372643 0.92 GPR119 (0.39) GPR119ACACBACACALNPEPRAB9A
SCHEMBL2218677 0.90 GPR119 (0.39) GPR119ACACBACACARAB9ANPC1
SCHEMBL2217078 0.89 GPR119 (0.40) GPR119ACACBACACARAB9ANPC1
SCHEMBL2217076 0.89 GPR119 (0.40) GPR119ACACBACACARAB9ANPC1
SCHEMBL2215997 0.88 ACACB (0.39) GPR119ACACBACACARAB9ANPC1
SCHEMBL2215991 0.88 ACACB (0.39) GPR119ACACBACACARAB9ANPC1
SCHEMBL2218046 0.86 GPR119 (0.39) GPR119ACACBACACARAB9ANPC1
SCHEMBL2218048 0.86 GPR119 (0.39) GPR119ACACBACACARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110178054-A1 Heterocyclic GPCR Agonists PROSIDION LIMITED (GB) 2011-07-21 US disclosed
US-20110178054-A1 Heterocyclic GPCR Agonists PROSIDION LIMITED (GB) 2011-07-21 US disclosed
US-20110178054-A1 Heterocyclic GPCR Agonists PROSIDION LIMITED (GB) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178054-A1 Heterocyclic GPCR Agonists GPR119, GCGR, GPR27 GPR119 1/4885ACACB 2654/4885ACACA 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.